From stem cell to immune effector: how adhesion, migration, and polarity shape T-cell and natural killer cell lymphocyte development in vitro and in vivo

From stem cell to immune effector: how adhesion, migration, and polarity shape T-cell and natural killer cell lymphocyte development in vitro and in vivo

Lymphocyte development is a posh and coordinated pathway originating from pluripotent stem cells throughout embryogenesis and persevering with whilst matured lymphocytes are primed and educated in grownup tissue. Hematopoietic stem cells develop in a specialised area of interest that features furthercellular matrix and supporting stromal and endothelial cells that each keep stem cell pluripotency and allow the era of differentiated cells. Cues for lymphocyte … Read more